Stereoselective reductive alkylation of 2,5-disubstituted pyrroles: a role for naphthalene in the partial reduction of heterocycles

Lithium in ammonia promotes the stereoselective reduction of 2,5- disubstituted pyrroles: such reactions proceed with good levels of stereoselectivity, producing the trans-isomer. The stereochemistry of one of the reduced compounds was proven by X-ray crystallography. A mechanism is proposed which e...

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Detalhes bibliográficos
Main Authors: Donohoe, T, Harji, R, Cousins, R
Formato: Journal article
Idioma:English
Publicado em: 2000