Stereoselective reductive alkylation of 2,5-disubstituted pyrroles: a role for naphthalene in the partial reduction of heterocycles
Lithium in ammonia promotes the stereoselective reduction of 2,5- disubstituted pyrroles: such reactions proceed with good levels of stereoselectivity, producing the trans-isomer. The stereochemistry of one of the reduced compounds was proven by X-ray crystallography. A mechanism is proposed which e...
| Auteurs principaux: | , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
2000
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