TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells

CD1d-restricted invariant natural killer T (iNKT) cells represent a heterogeneous population of lipid-reactive T cells that are involved in many immune responses, mediated through T-cell receptor (TCR)–dependent and/or independent activation. Although numerous microbial lipid antigens (Ags) have bee...

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Bibliographic Details
Main Authors: Paget, C, Deng, S, Soulard, D, Priestman, D, Speca, S, von Gerichten, J, Speak, A, Saroha, A, Pewzner-Jung, Y, Futerman, A, Mallevaey, T, Faveeuw, C, Gu, X, Platt, F, Sandhoff, R, Trottein, F
Format: Journal article
Published: Public Library of Science 2019