Perfused three-dimensional organotypic culture of human cancer cells for therapeutic evaluation

Pharmaceutical research requires pre-clinical testing of new therapeutics using both in-vitro and in vivo models. However, the species specificity of non-human in-vivo models and the inadequate recapitulation of physiological conditions in-vitro are intrinsic weaknesses. Here we show that perfusion...

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Bibliographic Details
Main Authors: Wan, X, Ball, S, Willenbrock, F, Yeh, S, Vlahov, N, Koennig, D, Green, M, Brown, G, Jeyaretna, S, Li, Z, Cui, Z, Ye, H, O'Neill, E
Format: Journal article
Published: Nature Publishing Group 2017