The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...

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Bibliographic Details
Main Authors: Van Bemmel, J, Galupa, R, Gard, C, Servant, N, Picard, C, Davies, J, Szempruch, A, Zhan, Y, Żylicz, J, Nora, E, Lameiras, S, De Wit, E, Gentien, D, Baulande, S, Giorgetti, L, Guttman, M, Hughes, J, Higgs, D, Gribnau, J, Heard, E
Format: Journal article
Language:English
Published: Springer Nature 2019