The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist
The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2019
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