Studies of the neurotoxicity of oral artemisinin derivatives in mice.

Intramuscular injections of high doses of the oil-soluble antimalarial artemisinin derivatives artemether and arteether produce an unusual pattern of selective damage to brain stem centers in experimental mammals, predominantly those involved in auditory processing and vestibular reflexes. We have s...

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Bibliographic Details
Main Authors: Nontprasert, A, Pukrittayakamee, S, Nosten-Bertrand, M, Vanijanonta, S, White, N
Format: Journal article
Language:English
Published: 2000