CDK9 inhibition activates innate immune response through viral mimicry

Cancer cells frequently exhibit hyperactivation of transcription, which can lead to increased sensitivity to compounds targeting the transcriptional kinases, in particular CDK9. However, mechanistic details of CDK9 inhibition‐induced cancer cell‐selective anti‐proliferative effects remain largely un...

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Bibliographic Details
Main Authors: Yalala, S, Gondane, A, Poulose, N, Liang, J, Mills, IG, Itkonen, HM
Format: Journal article
Language:English
Published: Wiley 2024