CDK9 inhibition activates innate immune response through viral mimicry

Cancer cells frequently exhibit hyperactivation of transcription, which can lead to increased sensitivity to compounds targeting the transcriptional kinases, in particular CDK9. However, mechanistic details of CDK9 inhibition‐induced cancer cell‐selective anti‐proliferative effects remain largely un...

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书目详细资料
Main Authors: Yalala, S, Gondane, A, Poulose, N, Liang, J, Mills, IG, Itkonen, HM
格式: Journal article
语言:English
出版: Wiley 2024