Association between polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers.

Central dopaminergic reward pathways give rise to dependence and are activated by nicotine. Allelic variants in genes involved in dopamine metabolism may therefore influence the amount of tobacco consumed by smokers. We developed assays for polymorphisms in dopamine beta-hydroxylase (DBH), monoamine...

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Bibliographic Details
Main Authors: McKinney, E, Walton, RT, Yudkin, P, Fuller, A, Haldar, N, Mant, D, Murphy, M, Welsh, K, Marshall, SE
Format: Journal article
Language:English
Published: 2000