Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial

Salmonella enterica serovar Typhi (S Typhi) is responsible for an estimated 20 million infections and 200 000 deaths each year in resource poor regions of the world. Capsular Vi-polysaccharide-protein conjugate vaccines (Vi-conjugate vaccines) are immunogenic and can be used from infancy but there a...

Full description

Bibliographic Details
Main Authors: Jin, C, Gibani, M, Moore, M, Juel, H, Jones, E, Meiring, J, Harris, V, Gardner, J, Nebykova, A, Kerridge, S, Hill, J, Thomaides-Brears, H, Blohmke, C, Yu, l, Angus, B, Pollard, A
Format: Journal article
Language:English
Published: Elsevier 2017