A large fraction of extragenic RNA pol II transcription sites overlap enhancers

Mammalian genomes are pervasively transcribed outside mapped protein-coding genes. One class of extragenic transcription products is represented by long non-coding RNAs (lncRNAs), some of which result from Pol_II transcription of bona-fide RNA genes. Whether all lncRNAs described insofar are product...

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Bibliographic Details
Main Authors: De Santa, F, Barozzi, I, Mietton, F, Ghisletti, S, Polletti, S, Tusi, B, Muller, H, Ragoussis, J, Wei, C, Natoli, G
Format: Journal article
Language:English
Published: Public Library of Science 2010