Post-translational site-selective protein backbone α-deuteration
Isotopic replacement has long-proven applications in small molecules. However, applications in proteins are largely limited to biosynthetic strategies or exchangeable (for example, N-H/D) labile sites only. The development of postbiosynthetic, C-1H → C-2H/D replacement in proteins could enable probi...
मुख्य लेखकों: | Galan, S, Wickens, J, Dadova, J, Ng, W, Zhang, X, Simion, R, Quinlan, R, Pires, E, Paton, R, Caddick, S, Chudasama, V, Davis, B |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
Springer Nature
2018
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समान संसाधन
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