Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.
BACKGROUND: Patients with diabetes mellitus are more prone to bacterial sepsis, but there are conflicting data on whether outcomes are worse in diabetics after presentation with sepsis. Glyburide is an oral hypoglycemic agent used to treat diabetes mellitus. This K(ATP)-channel blocker and broad-spe...
Hlavní autoři: | Koh, G, Maude, R, Schreiber, M, Limmathurotsakul, D, Wiersinga, W, Wuthiekanun, V, Lee, S, Mahavanakul, W, Chaowagul, W, Chierakul, W, White, N, van der Poll, T, Day, N, Dougan, G, Peacock, S |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2011
|
Podobné jednotky
-
Risk factors for recurrent melioidosis in northeast Thailand.
Autor: Limmathurotsakul, D, a další
Vydáno: (2006) -
Glyburide reduces bacterial dissemination in a mouse model of melioidosis.
Autor: Gavin C K W Koh, a další
Vydáno: (2013-01-01) -
Role and significance of quantitative urine cultures in diagnosis of melioidosis.
Autor: Limmathurotsakul, D, a další
Vydáno: (2005) -
Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis).
Autor: Koh, G, a další
Vydáno: (2011) -
Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei.
Autor: Wiersinga, W, a další
Vydáno: (2006)