Fold recognition and alignment in the ‘twilight zone’

<p>At present, the most accurate approach to predicting protein structure, comparative modelling, builds a model of a target sequence using known protein structures as templates. Comparative modelling becomes markedly less accurate in the ‘twilight zone’, where the target protein shares little...

Full description

Bibliographic Details
Main Authors: Hill, J, Jamie Hill
Other Authors: Deane, C
Format: Thesis
Language:English
Published: 2013
Subjects: