Retinal degeneration in choroideremia follows an exponential decay function

Fundus autofluorescence (AF) arises from lipofuscin, which is derived from retinoid byproducts of the visual cycle and accumulates within retinal pigment epithelial cells. Alterations in AF pattern are seen in a wide range of retinal degenerations. Choroideremia is an X-linked retinal dystrophy caus...

Full description

Bibliographic Details
Main Authors: Aylward, J, Xue, K, Patrício, M, Jolly, J, Wood, J, Brett, J, Jasani, K, MacLaren, R
Format: Journal article
Language:English
Published: Elsevier 2018