Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages

Genome engineering using CRISPR/Cas9 technology enables simple, efficient and precise genomic modifications in human cells. Conventional immortalized cell lines can be easily edited or screened using genome-wide libraries with lentiviral transduction. However, cell types derived from the differentia...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Navarro-Guerrero, E, Tay, C, Whalley, JP, Cowley, SA, Davies, B, Knight, JC, Ebner, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Springer Nature 2021