Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages

Genome engineering using CRISPR/Cas9 technology enables simple, efficient and precise genomic modifications in human cells. Conventional immortalized cell lines can be easily edited or screened using genome-wide libraries with lentiviral transduction. However, cell types derived from the differentia...

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Main Authors: Navarro-Guerrero, E, Tay, C, Whalley, JP, Cowley, SA, Davies, B, Knight, JC, Ebner, D
格式: Journal article
语言:English
出版: Springer Nature 2021