Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis
Tenascin-C (TNC), an extracellular matrix protein that has proinflammatory properties, is a recently described antibody target in rheumatoid arthritis (RA). In this study, we utilized a systematic discovery process and identified 5 potentially novel citrullinated TNC (cit-TNC) T cell epitopes. CD4+...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society for Clinical Investigation
2021
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