Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis

Tenascin-C (TNC), an extracellular matrix protein that has proinflammatory properties, is a recently described antibody target in rheumatoid arthritis (RA). In this study, we utilized a systematic discovery process and identified 5 potentially novel citrullinated TNC (cit-TNC) T cell epitopes. CD4+...

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Bibliographic Details
Main Authors: Song, J, Schwenzer, A, Midwood, KIM
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2021