Role of Base and nucleotide excision repair pathways in processing of clustered DNA lesions induced by ionising radiation

<p>Ionising radiation (IR) induces a wide spectrum of lesions in DNA, including double- and single-strand breaks, abasic (AP) sites and a variety of base lesions. IR-induced damage to DNA can range from simple, isolated lesions to clustered DNA damage in which multiple lesions are formed, usua...

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Bibliographic Details
Main Authors: Budworth, H, Budworth, Helen Louise
Format: Thesis
Language:English
Published: 2003
Subjects: