Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription

Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription

عرض إصدارات أخرى (1)

Chromosomal translocations and other abnormalities are central to the initiation of cancer in all cell types. Understanding the mechanism is therefore important to evaluate the evolution of cancer from the cancer initiating events to overt disease. Recent work has concentrated on model systems to de...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Ali, H, Daser, A, Dear, P, Wood, H, Rabbitts, P, Rabbitts, T
التنسيق:	Journal article
اللغة:	English
منشور في:	2013

مواد مشابهة

Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription.
حسب: Ali, H, وآخرون
منشور في: (2013)

Chromosomal translocation master genes, mouse models and experimental therapeutics.
حسب: Rabbitts, T
منشور في: (2001)

Chromosomal translocation products engender new intracellular therapeutic technologies.
حسب: Rabbitts, T, وآخرون
منشور في: (2003)

LMO2 at 25 years: a paradigm of chromosomal translocation proteins
حسب: Jennifer Chambers, وآخرون
منشور في: (2015-01-01)

The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism.
حسب: Collins, E, وآخرون
منشور في: (2002)

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer.
حسب: Forster, A, وآخرون
منشور في: (2003)

The role of LMO2 in development and in T cell leukemia after chromosomal translocation or retroviral insertion.
حسب: Nam, C, وآخرون
منشور في: (2006)

Chromosomal translocation engineering to recapitulate primary events of human cancer.
حسب: Forster, A, وآخرون
منشور في: (2005)

The versatile mixed lineage leukaemia gene MLL and its many associations in leukaemogenesis.
حسب: Daser, A, وآخرون
منشور في: (2005)

Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis.
حسب: Daser, A, وآخرون
منشور في: (2004)

Breakpoint structure of the <it>Anopheles gambiae </it>2R<it>b </it>chromosomal inversion
حسب: Costantini Carlo, وآخرون
منشور في: (2010-10-01)

FOXP1 abnormalities in lymphoma: translocation breakpoint mapping reveals insights into deregulated transcriptional control.
حسب: Goatly, A, وآخرون
منشور في: (2008)

FOXP1 abnormalities in lymphoma: Translocation breakpoint mapping reveals insights into deregulated transcriptional control
حسب: Goatly, A, وآخرون
منشور في: (2008)

Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis.
حسب: Drynan, L, وآخرون
منشور في: (2005)

Modeling chromosomal translocations using conditional alleles to recapitulate initiating events in human leukemias.
حسب: Lobato, M, وآخرون
منشور في: (2008)

Location of Balanced Chromosome-Translocation Breakpoints by Long-Read Sequencing on the Oxford Nanopore Platform
حسب: Liang Hu, وآخرون
منشور في: (2020-01-01)

ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.
حسب: Jiying Sun, وآخرون
منشور في: (2010-10-01)

Increased Resection at DSBs in G<sub>2</sub>-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ
حسب: Huaping Xiao, وآخرون
منشور في: (2022-07-01)

Identifying Balanced Chromosomal Translocations in Human Embryos by Oxford Nanopore Sequencing and Breakpoints Region Analysis
حسب: Zhenle Pei, وآخرون
منشور في: (2022-01-01)

Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites
حسب: Pierce Levi CT, وآخرون
منشور في: (2009-01-01)

Globozoospermic infertility associated with balanced DPY19L2 translocation/gene deletion at the chromosomal breakpoint
حسب: Yan-Wei Sha, وآخرون
منشور في: (2018-01-01)

Erratum: Interrogation of genomes by molecular copy-number counting (MCC) (Nature Methods (2006) vol. 3 (447-453))
حسب: Daser, A, وآخرون
منشور في: (2006)

Interrogation of genomes by molecular copy-number counting (MCC).
حسب: Daser, A, وآخرون
منشور في: (2006)

Genomic inverse PCR for exploration of ligated breakpoints (GIPFEL), a new method to detect translocations in leukemia.
حسب: Elisa Fueller, وآخرون
منشور في: (2014-01-01)

The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development.
حسب: McCormack, M, وآخرون
منشور في: (2003)

DISRUPTION OF THE GRPR GENE AND TRANSLOCATION BREAKPOINT SEQUENCE ASSOCIATED WITH MULTIPLE EXOSTOSES AND AUTISM
حسب: Ishikawabrush, Y, وآخرون
منشور في: (1995)

Mouse models of human chromosomal translocations and approaches to cancer therapy.
حسب: Rabbitts, T, وآخرون
منشور في: (2001)

Leukaemia lineage specification caused by cell-specific Mll-Enl translocations.
حسب: Cano, F, وآخرون
منشور في: (2008)

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.
حسب: Nicole Bennardo, وآخرون
منشور في: (2008-06-01)

Preclinical modeling of cytosine arabinoside response in Mll-Enl translocator mouse leukemias.
حسب: Cano, F, وآخرون
منشور في: (2008)

Chromosomal breakpoint mapping by arrayCGH using flow-sorted chromosomes
حسب: Imke M. Veltman, وآخرون
منشور في: (2003-11-01)

TOP1 and R-loops facilitate transcriptional DSBs at hypertranscribed cancer driver genes
حسب: Osama Hidmi, وآخرون
منشور في: (2024-03-01)

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.
حسب: Valentina Boeva, وآخرون
منشور في: (2013-01-01)

TICdb: a collection of gene-mapped translocation breakpoints in cancer
حسب: de Mendíbil Iñigo, وآخرون
منشور في: (2007-01-01)

Precise detection of rearrangement breakpoints in mammalian chromosomes
حسب: Gautier Christian, وآخرون
منشور في: (2008-06-01)

Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia.
حسب: Collins, E, وآخرون
منشور في: (2002)

Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis
حسب: Nadine Michel, وآخرون
منشور في: (2022-07-01)

Sequential gene targeting to make chimeric tumor models with de novo chromosomal abnormalities.
حسب: Chambers, J, وآخرون
منشور في: (2014)

Detection of Chromosome X;18 Breakpoints and Translocation of the Xq22.3;18q23 Regions Resulting in Variable Fertility Phenotypes
حسب: Attila Szvetko, وآخرون
منشور في: (2012-01-01)

Detection of chromosomal breakpoints in patients with developmental delay and speech disorders.
حسب: Kagistia H Utami, وآخرون
منشور في: (2014-01-01)