Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression.
Erythroid-specific DNase 1 hypersensitive sites have been identified at the promoters of the human alpha-like genes and within the region from 4 to 40 kb upstream of the gene cluster. One of these sites, HS-40, has been shown previously to be the major regulator of tissue-specific alpha-globin gene...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1993
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