Role of upstream DNase I hypersensitive sites in the regulation of human alpha globin gene expression.

Erythroid-specific DNase 1 hypersensitive sites have been identified at the promoters of the human alpha-like genes and within the region from 4 to 40 kb upstream of the gene cluster. One of these sites, HS-40, has been shown previously to be the major regulator of tissue-specific alpha-globin gene...

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Bibliographic Details
Main Authors: Sharpe, J, Summerhill, R, Vyas, P, Gourdon, G, Higgs, D, Wood, W
Format: Journal article
Language:English
Published: 1993