An approach to enzyme inhibition employing reversible boronate ester formation

Dynamic combinatorial chemistry (DCC) is a potentially useful method for the identification of biomacromolecule ligands; however, the number of reactions applicable to DCC in aqueous solution is limited. We report studies that investigate the reversible reaction of boronic acids with alcohols as an...

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Bibliographic Details
Main Authors: Leung, I, Jr, B, Schofield, C, Claridge, T, Brown, T
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2011
Subjects: