An approach to enzyme inhibition employing reversible boronate ester formation
Dynamic combinatorial chemistry (DCC) is a potentially useful method for the identification of biomacromolecule ligands; however, the number of reactions applicable to DCC in aqueous solution is limited. We report studies that investigate the reversible reaction of boronic acids with alcohols as an...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Royal Society of Chemistry
2011
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Subjects: |