An approach to enzyme inhibition employing reversible boronate ester formation
Dynamic combinatorial chemistry (DCC) is a potentially useful method for the identification of biomacromolecule ligands; however, the number of reactions applicable to DCC in aqueous solution is limited. We report studies that investigate the reversible reaction of boronic acids with alcohols as an...
Main Authors: | Leung, I, Jr, B, Schofield, C, Claridge, T, Brown, T |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Royal Society of Chemistry
2011
|
Subjects: |
Similar Items
-
NMR spectroscopy studies of enzyme function and inhibition
by: Khan, A
Published: (2016) -
The double CUE domain of chromatin remodelling factor SMARCAD1
by: West, P, et al.
Published: (2012) -
Structural insights into human SNF2/SWI2 chromatin remodeler SMARCAD1 and its role in DNA repair
by: Biasutto, A
Published: (2016) -
Multidimensional In Vivo NMR
by: Welch, J, et al.
Published: (2001) -
Mechanistic Studies on Histone Demethylases and Related Enzymes
by: Hopkinson, R
Published: (2013)