A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis.

Genetic susceptibility to multiple sclerosis is associated with genes of the major histocompatibility complex (MHC), particularly HLA-DRB1 and HLA-DQB1 (ref. 1). Both locus and allelic heterogeneity have been reported in this genomic region. To clarify whether HLA-DRB1 itself, nearby genes in the re...

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Bibliografske podrobnosti
Main Authors: Lincoln, MR, Montpetit, A, Cader, M, Saarela, J, Dyment, D, Tiislar, M, Ferretti, V, Tienari, P, Sadovnick, A, Peltonen, L, Ebers, G, Hudson, T
Format: Journal article
Jezik:English
Izdano: 2005

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