Restriction site-specific methylation studies of imprinted genes with quantitative real-time PCR.

BACKGROUND: Epigenetic studies, such as the measurement of DNA methylation, are important in the investigation of syndromes influenced by imprinted genes. Quick and accurate quantification of methylation at such genes can be of appreciable diagnostic aid. METHODS: We first digested genomic DNA with...

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Bibliographic Details
Main Authors: Bruce, S, Hannula-Jouppi, K, Lindgren, C, Lipsanen-Nyman, M, Kere, J
Format: Journal article
Language:English
Published: 2008