Investigating the systemic pathological mechanisms of FUS and TDP-43
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal neurodegenerative disorders (NDDs), with no cures. These conditions sit on a spectrum and have overlapping clinical symptoms, genetics and pathology. In particular, FUS and TDP-43 inclusions have been observed in familia...
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Format: | Thesis |
Language: | English |
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2022
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