Small molecules as tools to study the chemical epigenetics of lysine acetylation
Lysine acetylation has emerged as a key post-translational modification found at many sites throughout the cell. It plays an important role in epigenetic processes, and more generally in the regulation of protein stability and interactions. Acetyl groups are installed by lysine acetyltransferases an...
Main Authors: | Schiedel, M, Conway, S |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2018
|
Similar Items
-
Targeting bromodomains: epigenetic readers of lysine acetylation.
by: Filippakopoulos, P, et al.
Published: (2014) -
Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions.
by: Hewings, D, et al.
Published: (2012) -
Cracking the histone code: Developing inhibitors of bromodomain-acetyl-lysine interactions
by: Conway, S
Published: (2013) -
Chemical epigenetics: the impact of chemical and chemical biology techniques on bromodomain target validation
by: Schiedel, M, et al.
Published: (2019) -
Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation
by: Bryson, Bryan D., et al.
Published: (2015)