Small molecules as tools to study the chemical epigenetics of lysine acetylation

Lysine acetylation has emerged as a key post-translational modification found at many sites throughout the cell. It plays an important role in epigenetic processes, and more generally in the regulation of protein stability and interactions. Acetyl groups are installed by lysine acetyltransferases an...

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Bibliographic Details
Main Authors: Schiedel, M, Conway, S
Format: Journal article
Language:English
Published: Elsevier 2018