The quaternary architecture of RARβ–RXRα heterodimer facilitates domain–domain signal transmission

Assessing the physical connections and allosteric communications in multi-domain nuclear receptor (NR) polypeptides has remained challenging, with few crystal structures available to show their overall structural organizations. Here we report the quaternary architecture of multi-domain retinoic acid...

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Bibliographic Details
Main Authors: Chandra, V, Wu, D, Li, S, Potluri, N, Kim, Y, Rastinejad, F
Format: Journal article
Language:English
Published: Springer Nature 2017