Low penetrance breast cancer predisposition SNPs are site specific.

Large scale association studies have identified low penetrance susceptibility alleles that predispose to breast cancer. A locus on chromosome 8q24.21 has been shown to harbour variants that predispose to breast, ovarian, colorectal and prostate cancer. The finding of risk variants clustering at 8q24...

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Autors principals: Mcinerney, N, Colleran, G, Rowan, A, Walther, A, Barclay, E, Spain, S, Jones, A, Tuohy, S, Curran, C, Miller, N, Kerin, M, Tomlinson, I, Sawyer, E
Format: Journal article
Idioma:English
Publicat: 2009