OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.

2-Oxoglutarate (2OG) and Fe(II)-dependent oxygenase domain-containing protein 1 (OGFOD1) is predicted to be a conserved 2OG oxygenase, the catalytic domain of which is related to hypoxia-inducible factor prolyl hydroxylases. OGFOD1 homologs in yeast are implicated in diverse cellular functions rangi...

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Dettagli Bibliografici
Autori principali: Singleton, R, Liu-Yi, P, Formenti, F, Ge, W, Sekirnik, R, Fischer, R, Adam, J, Pollard, P, Wolf, A, Thalhammer, A, Loenarz, C, Flashman, E, Yamamoto, A, Coleman, M, Kessler, B, Wappner, P, Schofield, C, Ratcliffe, P, Cockman, M
Natura: Journal article
Lingua:English
Pubblicazione: National Academy of Sciences 2014