Structural characterization of an anti-gp120 RNA aptamer that neutralizes R5 strains of HIV-1
We recently described the isolation of 2′-fluoropyrimidine-substituted RNA aptamers that bind specifically to the surface glycoprotein (gp 120) of the R5 strain, HIV-1Ba-L, as presented in a previous study. These aptamers potently neutralize HIV-1 infectivity in human peripheral blood mononuclear ce...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Cold Spring Harbor Laboratory Press
2005
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