Inhibitors of the FEZ-1 metallo-beta-lactamase.

Metallo-beta-lactamases (MBLs) catalyze the hydrolysis of beta-lactams including penicillins, cephalosporins and carbapenems. Starting from benzohydroxamic acid (1) structure-activity studies led to the identification of selective inhibitors of the FEZ-1 MBL, e.g., 2,5-substituted benzophenone hydro...

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書目詳細資料
Main Authors: Liénard, B, Horsfall, L, Galleni, M, Frère, J, Schofield, C
格式: Journal article
語言:English
出版: 2007