Integrating single-cell and spatial transcriptomics in a computational multiscale model of triple negative breast cancer
<p>This thesis presents a multiscale computational model of tumour growth, microCJ. microCJ models cells as independent agents, each with their own genetic identity and state. For each cell in the simulation, a Boolean gene regulatory network is iterated, the outputs of which govern the action...
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Format: | Disertacija |
Jezik: | English |
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2022
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