Integrating single-cell and spatial transcriptomics in a computational multiscale model of triple negative breast cancer

<p>This thesis presents a multiscale computational model of tumour growth, microCJ. microCJ models cells as independent agents, each with their own genetic identity and state. For each cell in the simulation, a Boolean gene regulatory network is iterated, the outputs of which govern the action...

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Bibliografski detalji
Glavni autor: Victori, P
Daljnji autori: Buffa, F
Format: Disertacija
Jezik:English
Izdano: 2022
Teme: