Specific inhibition of PI3K p110δ inhibits CSF‐1‐induced macrophage spreading and invasive capacity

Colony stimulating factor‐1 (CSF‐1) stimulates mononuclear phagocytic cell survival, growth and differentiation into macrophages through activation and autophosphorylation of the CSF‐1 receptor (CSF‐1R). We have previously demonstrated that CSF‐1‐induced phosphorylation of Y721 (pY721) in the recept...

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Bibliographic Details
Main Authors: Mouchemore, KA, Sampaio, N, Murrey, MW, Stanley, ER, Lannutti, BJ, Pixley, FJ
Format: Journal article
Language:English
Published: Wiley 2013