The effect of the Interleukin-6-174G > C promoter gene polymorphism on endothelial function in healthy volunteers.

AIMS: Atherosclerosis is a chronic inflammatory condition, manifest in its early stages by endothelial dysfunction. Interleukin-6 (IL6) plays a key role in driving this process through stimulation of acute phase protein synthesis. We have examined the effect of the IL6 gene -174G > C promoter...

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Bibliographic Details
Main Authors: Brull, D, Leeson, C, Montgomery, H, Mullen, M, deDivitiis, M, Humphries, SE, Deanfield, J, Lesson, C
Format: Journal article
Language:English
Published: 2002