Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements

Sparse profiling of CpG methylation in blood by microarrays has identified epigenetic links to common diseases. Here we apply methylC-capture sequencing (MCC-Seq) in a clinical population of ~200 adipose tissue and matched blood samples (Ntotal~400), providing high-resolution methylation profiling (...

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Bibliographic Details
Main Authors: Allum, F, Hedman, Å, Shao, X, Cheung, W, Vijay, J, Guénard, F, Kwan, T, Simon, M, Ge, B, Moura, C, Boulier, E, Rönnblom, L, Bernatsky, S, Lathrop, M, McCarthy, M, Deloukas, P, Tchernof, A, Pastinen, T, Vohl, M, Grundberg, E
Format: Journal article
Language:English
Published: Springer Nature 2019