A population of in silico models to face the variability of human induced pluripotent stem cell-derived cardiomyocytes: the hERG block case study

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are characterized by an extreme variability, which cannot be reproduced by a single in silico model. Here we present a population of hiPSC-CM models, calibrated using six different experimental datasets. By sampling the maximum c...

Full description

Bibliographic Details
Main Authors: Paci, M, Passini, E, Severi, S, Hyttinen, J, Rodriguez, B
Format: Conference item
Published: IEEE 2017