Evolution of a polymorphic regulatory element in interferon-gamma through transposition and mutation.

Mammalian transposable elements have intrinsic regulatory elements that can activate neighboring genes, and it is speculated that they can also carry extrinsic transactivating DNA sequences to new genomic locations. We have identified a polymorphic segment of the human interferon-gamma promoter regi...

Full description

Bibliographic Details
Main Authors: Ackerman, H, Udalova, I, Hull, J, Kwiatkowski, D
Format: Journal article
Language:English
Published: 2002