SpyRings declassified: a blueprint for using isopeptide-mediated cyclization to enhance enzyme thermal resilience
Enzymes often have marginal stability, with unfolding typically leading to irreversible denaturation. This sensitivity is a major barrier, both for de novo enzyme development and for expanding enzyme impact beyond the laboratory. Seeking an approach to enhance resilience to denaturation that could b...
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| Format: | Journal article |
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Elsevier
2016
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