Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery.
Apoptosis of neurons plays fundamental roles in brain development and disease. Although neurons share with other cell types components of the mitochondrial apoptotic machinery, how this machinery is specifically activated in neurons remains poorly understood. Remarkably, phosphorylation of the BH3-o...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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