Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay
The megakaryocyte/erythroid Transient Myeloproliferative Disorder (TMD) in newborns with Down Syndrome (DS) occurs when N-terminal truncating mutations of the hemopoietic transcription factor GATA1, that produce GATA1short protein (GATA1s), are acquired early in development. Prior work has shown tha...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Ferrara Storti Foundation
2020
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