Variation across the allele frequency spectrum.

Variation across the allele frequency spectrum.

A new study finds that individuals with high plasma triglyceride levels carry approximately twice as many rare, coding genetic variants within four candidate genes identified through genome-wide association studies than individuals without these high levels. This study demonstrates the overlap of ra...

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Bibliografiske detaljer
Main Authors:	Gloyn, A, McCarthy, M
Format:	Journal article
Sprog:	English
Udgivet:	2010

Lignende værker

Understanding the genetic complexity of puberty timing across the allele frequency spectrum
af: Kentistou, KA, et al.
Udgivet: (2023)

Asymptotics of the allele frequency spectrum associated with the Bolthausen-Sznitman coalescent
af: Basdevant, A, et al.
Udgivet: (2008)

Quantifying variations associated with dental caries reveals disparity in effect allele frequencies across diverse populations
af: Sangram Sandhu, et al.
Udgivet: (2024-06-01)

Exploring the unknown: assumptions about allelic architecture and strategies for susceptibility variant discovery.
af: McCarthy, M
Udgivet: (2009)

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus
af: Travers, M, et al.
Udgivet: (2010)

Introgression in the genus Campylobacter: generation and spread of mosaic alleles.
af: Sheppard, S, et al.
Udgivet: (2011)

Genetics for Endocrinologists: The Molecular Genetic Basis of Endocrine Disorders.
af: McCarthy, M, et al.
Udgivet: (2003)

The genetics of type 2 diabetes.
af: Gloyn, A, et al.
Udgivet: (2001)

Genetics: how the UKPDS contributed to determining the genetic landscape of Type 2 diabetes.
af: Gloyn, A, et al.
Udgivet: (2008)

Preface
af: Gloyn, A, et al.
Udgivet: (2014)

A Computational Approach for Modeling the Allele Frequency Spectrum of Populations with Arbitrarily Varying Size
af: Hua Chen
Udgivet: (2019-12-01)

Kernel density estimation of allele frequency including undetected alleles
af: Satoshi Aoki, et al.
Udgivet: (2024-04-01)

The importance of context: uncovering species- and tissue-specific effects of genetic risk variants for type 2 diabetes
af: Thomsen, S, et al.
Udgivet: (2016)

BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study
af: Louwers, Y, et al.
Udgivet: (2014)

Measuring growth and obesity across childhood and adolescence
af: McCarthy, H. David
Udgivet: (2014)

Genomic variation in human health and disease
af: McCarthy, D
Udgivet: (2015)

TCF7L2 and diabetes: a tale of two tissues, and of two species.
af: McCarthy, M, et al.
Udgivet: (2013)

Can one learn history from the allelic spectrum?
af: Myers, S, et al.
Udgivet: (2008)

Large-scale type 2 diabetes association analysis of low-frequency nonsynonymous coding variants in the HNF4A gene including up to 17,600 individuals
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Udgivet: (2008)

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to Type 2 diabetes
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Udgivet: (2009)

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.
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Udgivet: (2009)

Determining SNP Allele Frequencies in DNA Pools
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Udgivet: (2000-03-01)

Polymorphism specific Allele Frequencies on Cervical Cancer
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Udgivet: (2024-07-01)

The impact of rare variation on gene expression across tissues
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Udgivet: (2017)

Role of low frequency variants in HNF1A exons 8-10 encoding hepatocyte nuclear factor-1 alpha isoform A to susceptibility to Type 2 diabetes
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Udgivet: (2010)

coiaf: Directly estimating complexity of infection with allele frequencies.
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Udgivet: (2023-06-01)

Distribution of BoLA-DRB3 Allelic Frequencies and Identification of Two New Alleles in Iranian Buffalo Breed
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Udgivet: (2012-01-01)

Frequencies of HLA-B alleles in Indonesian Malay Ethnic
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Udgivet: (2024-03-01)

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic beta cells
af: Thomsen, S, et al.
Udgivet: (2018)

Allelic expression of deleterious protein-coding variants across human tissues.
af: Kimberly R Kukurba, et al.
Udgivet: (2014-05-01)

The Low Frequency Edge Oscillation in Alcator C-Mod and ASDEX Upgrade I-Mode
af: McCarthy, William C.
Udgivet: (2022)

Drugs across the spectrum /
af: 328298 Goldberg, Raymond
Udgivet: (2006)

AlleleShift: an R package to predict and visualize population-level changes in allele frequencies in response to climate change
af: Roeland Kindt
Udgivet: (2021-06-01)

The population genetics of sporophytic self-incompatibility in Senecio squalidus L. (Asteraceae): the number, frequency, and dominance interactions of S alleles across its British range.
af: Brennan, A, et al.
Udgivet: (2006)

Expanding the allelic spectrum of ELOVL4‐related autosomal recessive neuro‐ichthyosis
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Udgivet: (2023-12-01)

Allele Frequencies of Genetic Variants Associated with Varroa Drone Brood Resistance (DBR) in <i>Apis mellifera</i> Subspecies across the European Continent
af: Regis Lefebre, et al.
Udgivet: (2024-06-01)

Allele frequencies of fifteen STRs in a representative sample of the Italian population.
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Udgivet: (2009)

Increased Frequency of Complement C4 "Null" Alleles in Autoimmune Hepatitis
af: Eman S. AL-Obeidy, et al.
Udgivet: (2009-10-01)

Quantitative traits associated with the Type 2 diabetes susceptibility allele in Kir6.2.
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Udgivet: (2003)

Association of rheumatoid arthritis with an amino acid allelic variation of the T cell receptor.
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