The influence of geometry, surface character, and flexibility on the permeation of ions and water through biological pores.
A hydrophobic constriction site can act as an efficient barrier to ion and water permeation if its diameter is less than the diameter of an ion's first hydration shell. This hydrophobic gating mechanism is thought to operate in a number of ion channels, e.g. the nicotinic receptor, bacterial me...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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