Asymmetric synthesis of cyclic beta-amino acids and cyclic amines via sequential diastereoselective conjugate addition and ring closing metathesis

Asymmetric synthesis of cyclic beta-amino acids and cyclic amines via sequential diastereoselective conjugate addition and ring closing metathesis

Diastereoselective conjugate addition of lithium (S)-N-allyl-N-α-methylbenzylamide to a range of α,β-unsaturated esters followed by ring closing metathesis is used to afford efficiently a range of substituted cyclic β-amino esters in high d.e. Alternatively, conjugate addition to α,β-unsaturated Wei...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Chippindale, A, Davies, S, Iwamoto, K, Parkin, R, Smethurst, C, Smith, A, Rodriguez-Solla, H
Formatua:	Journal article
Argitaratua:	2003

Antzeko izenburuak

Ring closing metathesis for the asymmetric synthesis of (S)-homopipecolic acid, (S)-homoproline and (S)-coniine
nork: Davies, S, et al.
Argitaratua: (2002)

Diastereoselective synthesis of P-stereogenic heterocycles via enyne ring-closing metathesis.
nork: Harvey, J, et al.
Argitaratua: (2010)

Diastereoselective ring-closing metathesis/nucleophilic ring-opening approach to P-stereogenic phosphine oxides
nork: Dunne, K, et al.
Argitaratua: (2006)

A Highly Efficient and Practical Synthesis of Cyclic Phosphinates Using Ring-Closing Metathesis.
nork: Bujard, M, et al.
Argitaratua: (1999)

Divergent synthesis of cyclic ketones via a ring-closing metathesis and oxidation method
nork: Jorge Cruz-Huerta, et al.
Argitaratua: (2025-01-01)

New chiral molybdenum metathesis catalysts : application to the enantioselective preparation of cyclic amines
nork: Dolman, Sarah Jennifer, 1977-
Argitaratua: (2005)

Diastereoselective ring-closing metathesis: synthesis of P-stereogenic phosphinates from prochiral phosphinic acid derivatives.
nork: Dunne, K, et al.
Argitaratua: (2005)

Ligand variation in molybdenum asymmetric ring-closing metathesis catalysts
nork: Jamieson, Jennifer Yvonne, 1975-
Argitaratua: (2009)

Catalytic enantio- and diastereoselective alkylations with cyclic sulfamidates.
nork: Moss, T, et al.
Argitaratua: (2010)

Borane-catalyzed cross-metathesis strategy for facile transformation of cyclic (alkyl)(amino)germylenes
nork: Rao, Bin, et al.
Argitaratua: (2021)

Diastereoselective conjugate reduction with samarium diiodide: asymmetric synthesis of methyl (2S,3R)-N-acetyl-2-amino-2,3-dideuterio-3-phenylpropionate.
nork: Davies, S, et al.
Argitaratua: (2004)

Highly diastereoselective electrophilic fluorination of cyclic syn-beta-hydroxysilanes
nork: Purser, S, et al.
Argitaratua: (2007)

Ring closing metathesis of phenyl-substituted dienes
nork: Bujard, M, et al.
Argitaratua: (1999)

Chiral molybdenum and tungsten imido alkylidene complexes as catalysts for asymmetric ring-closing metathesis (ARCM)
nork: Alexander, John Bryson, 1972-
Argitaratua: (2009)

Lead-mediated highly diastereoselective allylation of aldehydes with cyclic allylic halides
nork: Cheng, Bu-Qing, et al.
Argitaratua: (2021)

Enantioselective synthesis of P-stereogenic phosphinates and phosphine oxides by molybdenum-catalyzed asymmetric ring-closing metathesis.
nork: Harvey, J, et al.
Argitaratua: (2009)

Kinetically E-selective macrocyclic ring-closing metathesis
nork: Shen, Xiao, et al.
Argitaratua: (2018)

Ring-closing metathesis: Novel routes to aromatic heterocycles
nork: Donohoe, T, et al.
Argitaratua: (2008)

Ring-closing metathesis: novel routes to aromatic heterocycles.
nork: Donohoe, T, et al.
Argitaratua: (2008)

Highly diastereoselective and stereodivergent dihydroxylations of acyclic allylic amines: application to the asymmetric synthesis of 3,6-dideoxy-3-amino-L-talose.
nork: Csatayová, K, et al.
Argitaratua: (2011)

Cyclic beta-amino acid derivatives: synthesis via lithium amide promoted tandem asymmetric conjugate addition-cyclisation reactions.
nork: Davies, S, et al.
Argitaratua: (2005)

Iron-mediated highly diastereoselective allylation of carbonyl compounds with cyclic allylic halides
nork: Liu, Xuan-Yu, et al.
Argitaratua: (2021)

Zwitterionic bis(phenolate)amine lanthanide complexes for the ring-opening polymerisation of cyclic esters.
nork: Dyer, H, et al.
Argitaratua: (2008)

Endo-Selective Enyne Ring-Closing Metathesis Promoted by Stereogenic-at-Mo Monoalkoxide and Monoaryloxide Complexes. Efficient Synthesis of Cyclic Dienes Not Accessible throught Reactions with Ru Carbenes
nork: Lee, Yeon-Ju, et al.
Argitaratua: (2013)

Ring-closing metathesis as a basis for the construction of aromatic compounds.
nork: Donohoe, T, et al.
Argitaratua: (2006)

Ring-closing olefin metathesis for the synthesis of phosphorus containing heterocycles
nork: Hetherington, L, et al.
Argitaratua: (2000)

Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis
nork: Jakubec, P, et al.
Argitaratua: (2011)

Synthesis of substituted pyridines and pyridazines via ring closing metathesis.
nork: Donohoe, T, et al.
Argitaratua: (2009)

Asymmetric syntheses of dihydroxyhomoprolines via doubly diastereoselective lithium amide conjugate addition reactions
nork: Davies, S, et al.
Argitaratua: (2013)

Chemo- and diastereoselective cyclopropanation of allylic amines and carbamates
nork: Csatayova, K, et al.
Argitaratua: (2010)

ASYMMETRIC-SYNTHESIS OF BETA-AMINO-ALPHA-HYDROXY ACIDS VIA DIASTEREOSELECTIVE HYDROXYLATION OF HOMOCHIRAL BETA-AMINO ENOLATES
nork: Bunnage, M, et al.
Argitaratua: (1994)

Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines
nork: Donohoe, T, et al.
Argitaratua: (2009)

Tandem ring-closing metathesis/isomerization reactions for the total synthesis of violacein
nork: Petersen, Mette T., et al.
Argitaratua: (2013)

One-pot conversions of olefins to cyclic carbonates and secondary allylic and homoallylic amines to cyclic carbamates.
nork: Davies, S, et al.
Argitaratua: (2010)

Bismuth-mediated diastereoselective allylation reaction of carbonyl compounds with cyclic allylic halides or cinnamyl halide
nork: Liu, Xuan-Yu, et al.
Argitaratua: (2021)

Copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents to cyclic enones to form quaternary centers.
nork: Roth, P, et al.
Argitaratua: (2014)

Ring-closing iodoamination of homoallylic amines for the synthesis of polysubstituted pyrrolidines: application to the asymmetric synthesis of (-)-codonopsinine
nork: Davies, S, et al.
Argitaratua: (2012)

Novel synthesis of borane complexes of cyclic phosphanes using ruthenium-catalyzed olefin metathesis
nork: Schuman, M, et al.
Argitaratua: (2000)

Ammonium-directed oxidation of cyclic allylic and homoallylic amines.
nork: Bond, C, et al.
Argitaratua: (2009)

Oxidative β-C–H sulfonylation of cyclic amines
nork: Griffiths, RJ, et al.
Argitaratua: (2018)