The synthesis of (-)-cis- and (-)-trans-crobarbatic acid

The synthesis of both cis- and trans-crobarbatic acid is reported. The five-step sequence proceeds in high yield and with control of both relative and absolute stereochemistry. The key step in the synthesis is the Birch reductive alkylation of a chiral furoic acid which sets the absolute stereochemi...

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Bibliographic Details
Main Authors: Donohoe, T, Stevenson, C, Helliwell, M, Irshad, R, Ladduwahetty, T
Format: Journal article
Language:English
Published: 1999