Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity.

Serine proteases in the adult CNS contribute both to activity-dependent structural changes accompanying learning and to the regulation of excitotoxic cell death. Brain serine protease 1 (BSP1)/neuropsin is a trypsin-like serine protease exclusively expressed, within the CNS, in the hippocampus and a...

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Bibliographic Details
Main Authors: Davies, B, Kearns, I, Ure, J, Davies, C, Lathe, R
Format: Journal article
Language:English
Published: 2001