Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity.
Serine proteases in the adult CNS contribute both to activity-dependent structural changes accompanying learning and to the regulation of excitotoxic cell death. Brain serine protease 1 (BSP1)/neuropsin is a trypsin-like serine protease exclusively expressed, within the CNS, in the hippocampus and a...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2001
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