CRTH2 expression on T cells in asthma.

Mast cell-derived prostaglandin D2 (PGD2) is the major prostanoid found within the airway of asthmatics immediately following allergen challenge. PGD2 has been shown to have chemokinetic effects on eosinophils and T helper type 2 (Th2) cells in vitro. This occurs through the interaction of PGD2 with...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Mutalithas, K, Guillen, C, Day, C, Brightling, C, Pavord, I, Wardlaw, A
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2010