Oocytes as an expression system for studying receptor/channel targets of drugs and pesticides.

Oocytes as an expression system for studying receptor/channel targets of drugs and pesticides.

The Xenopus laevis oocyte offers one of the most convenient expression systems for assaying the actions of candidate ligands on cloned ionotropic neurotransmitter receptors (also known as ligand-gated ion channels [LGICs]). Their large size makes injection of complementary ribonucleic acid or comple...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Buckingham, S, Pym, L, Sattelle, D
פורמט:	Journal article
שפה:	English
יצא לאור:	2006

פריטים דומים

Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics.
מאת: Sattelle, D, et al.
יצא לאור: (2007)

Subtype-specific actions of beta-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4) expressed in Xenopus laevis oocytes.
מאת: Pym, L, et al.
יצא לאור: (2005)

Subtype-specific actions of β-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (α7, α4β2, α3β4) expressed in Xenopus laevis oocytes
מאת: Pym, L, et al.
יצא לאור: (2005)

Nicotinic acetylcholine receptors as drug/chemical targets: contributions from comparative genomics, forward and reverse genetics
מאת: Sattelle, D, et al.
יצא לאור: (2005)

Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides.
מאת: Buckingham, S, et al.
יצא לאור: (2005)

The Abeta1-42M35C mutated amyloid peptide Abeta1-42 and the 25-35 fragment fail to mimic the subtype-specificity of actions on recombinant human nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4).
מאת: Pym, L, et al.
יצא לאור: (2007)

Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study.
מאת: Brown, L, et al.
יצא לאור: (2006)

Actions of agonists, fipronil and ivermectin on the predominant in vivo splice and edit variant (RDLbd, I/V) of the Drosophila GABA receptor expressed in Xenopus laevis oocytes.
מאת: Kristin Lees, et al.
יצא לאור: (2014-01-01)

Nicotinic acetylcholine receptors as targets for anthelmintics - Genetic, genomic and functional studies
מאת: Buckingham, S, et al.
יצא לאור: (2006)

A7DB: a relational database for mutational, physiological and pharmacological data related to the α7 nicotinic acetylcholine receptor
מאת: Buckingham, S, et al.
יצא לאור: (2005)

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans
מאת: Glendinning, S, et al.
יצא לאור: (2011)

Allosteric modulation by benzodiazepines of GABA-gated chloride channels of an identified insect motor neurone.
מאת: Buckingham, S, et al.
יצא לאור: (2009)

Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons.
מאת: Jones, A, et al.
יצא לאור: (2010)

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.
מאת: Buckingham, S, et al.
יצא לאור: (2009)

Invertebrate studies and their ongoing contributions to neuroscience.
מאת: Sattelle, D, et al.
יצא לאור: (2006)

Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits.
מאת: Jones, A, et al.
יצא לאור: (2009)

Bicuculline-insensitive GABA-gated Cl- channels in the larval nervous system of the moth Manduca sexta.
מאת: Sattelle, D, et al.
יצא לאור: (2003)

Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency.
מאת: Hosie, A, et al.
יצא לאור: (2001)

A7DB: a relational database for mutational, physiological and pharmacological data related to the α7 nicotinic acetylcholine receptor
מאת: Sansom Mark SP, et al.
יצא לאור: (2005-01-01)

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits.
מאת: Williamson, S, et al.
יצא לאור: (2009)

Splice-variant- and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency.
מאת: Jones, A, et al.
יצא לאור: (2009)

Neonicotinoid insecticides display partial and super agonist actions on native insect nicotinic acetylcholine receptors.
מאת: Brown, L, et al.
יצא לאור: (2006)

Replacement of asparagine with arginine at the extracellular end of the second transmembrane (M2) region of insect GABA receptors increases sensitivity to penicillin G.
מאת: Hosie, A, et al.
יצא לאור: (2006)

Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms.
מאת: Buckingham, S, et al.
יצא לאור: (2005)

Fast, automated measurement of nematode swimming (thrashing) without morphometry
מאת: Buckingham, S, et al.
יצא לאור: (2009)

Strategies for automated analysis of C. elegans locomotion.
מאת: Buckingham, S, et al.
יצא לאור: (2008)

Xenopus oocytes as a heterologous expression system for studying ion channels with the patch-clamp technique.
מאת: Tammaro, P, et al.
יצא לאור: (2008)

A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.
מאת: Jones, A, et al.
יצא לאור: (2011)

Expression and Analysis of Flow-regulated Ion Channels in Xenopus Oocytes
מאת: Shujie Shi, et al.
יצא לאור: (2017-04-01)

Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors.
מאת: Matsuda, K, et al.
יצא לאור: (2001)

Actions of snake neurotoxins on an insect nicotinic cholinergic synapse.
מאת: Hue, B, et al.
יצא לאור: (2007)

Voltage gated potassium channels expressed in Xenopus laevis(AMPHIBIA) oocytes
מאת: Hedna Chaves, et al.
יצא לאור: (2003-01-01)

Chemistry-to-gene screens in Caenorhabditis elegans.
מאת: Jones, A, et al.
יצא לאור: (2005)

Insect genomes: challenges and opportunities for neuroscience.
מאת: Sattelle, D, et al.
יצא לאור: (2007)

Impact of oocytes with CLCG on ICSI outcomes and their potential relation to pesticide exposure
מאת: Philippe Merviel, et al.
יצא לאור: (2017-07-01)

Differential effects of ethanol on electrical properties of various potassium channels expressed in oocytes.
מאת: Anantharam, V, et al.
יצא לאור: (1992)

Expression of the cloned beta-cell ATP-sensitive potassium channel in Xenopus oocytes
מאת: Gribble, F, et al.
יצא לאור: (1996)

Sheep oocyte expresses leptin and functional leptin receptor mRNA
מאת: Seyyed Jalil Taheri, et al.
יצא לאור: (2016-09-01)

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.
מאת: Sattelle, D, et al.
יצא לאור: (2009)

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits.
מאת: Sally M Williamson, et al.
יצא לאור: (2009-07-01)