TonB-dependent receptor repertoire of pseudomonas aeruginosa for uptake of siderophore-drug conjugates

The conjugation of siderophores to antimicrobial molecules is an attractive strategy to overcome the low outer membrane permeability of Gram-negative bacteria. In this Trojan horse approach, the transport of drug conjugates is redirected via TonB-dependent receptors (TBDR), which are involved in the...

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Bibliographic Details
Main Authors: Luscher, A, Moynié, L, Auguste, P, Bumann, D, Mazza, L, Pletzer, D, Naismith, J, Köhler, T
Format: Journal article
Language:English
Published: American Society for Microbiology 2018