Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A.

Neutrophils are the main effector cells during inflammation, but they can also control excessive inflammatory responses by secreting anti-inflammatory cytokines. However, the mechanisms that modulate their plasticity remain unclear. We now show that systemic serum amyloid A 1 (SAA-1) controls the pl...

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Bibliographic Details
Main Authors: De Santo, C, Arscott, R, Booth, S, Karydis, I, Jones, M, Asher, R, Salio, M, Middleton, M, Cerundolo, V
Format: Journal article
Language:English
Published: 2010